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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

Potassium (K(+)) channels are transmembrane proteins that passively and selectively allow K(+) ions to flow through them, after opening in response to an external stimulus. One of the most critical functional aspects of their function is their ability to remain very selective for K(+) over Na(+) whi...

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Detalles Bibliográficos
Publicado en:Biochim Biophys Acta
Main Authors: Medovoy, David, Perozo, Eduardo, Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939264/
https://ncbi.nlm.nih.gov/pubmed/26896693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.02.019
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