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Probing the Energy Landscape of Activation Gating of the Bacterial Potassium Channel KcsA

The bacterial potassium channel KcsA, which has been crystallized in several conformations, offers an ideal model to investigate activation gating of ion channels. In this study, essential dynamics simulations are applied to obtain insights into the transition pathways and the energy profile of KcsA...

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Detalhes bibliográficos
Main Authors: Linder, Tobias, de Groot, Bert L., Stary-Weinzinger, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642040/
https://ncbi.nlm.nih.gov/pubmed/23658510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003058
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