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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

Potassium (K(+)) channels are transmembrane proteins that passively and selectively allow K(+) ions to flow through them, after opening in response to an external stimulus. One of the most critical functional aspects of their function is their ability to remain very selective for K(+) over Na(+) whi...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Medovoy, David, Perozo, Eduardo, Roux, Benoît
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939264/
https://ncbi.nlm.nih.gov/pubmed/26896693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.02.019
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