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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

Potassium (K(+)) channels are transmembrane proteins that passively and selectively allow K(+) ions to flow through them, after opening in response to an external stimulus. One of the most critical functional aspects of their function is their ability to remain very selective for K(+) over Na(+) whi...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Medovoy, David, Perozo, Eduardo, Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939264/
https://ncbi.nlm.nih.gov/pubmed/26896693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.02.019
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