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Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating
In K(+) channels, the selectivity filter, pore helix, and outer vestibule play a crucial role in gating mechanisms. The outer vestibule is an important structurally extended region of KcsA in which toxins, blockers, and metal ions bind and modulate the gating behavior of K(+) channels. Despite its f...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918809/ https://ncbi.nlm.nih.gov/pubmed/24429344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314875111 |
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