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Rapid Intracellular TEA Block of the KcsA Potassium Channel

Intracellular tetraethylammonium (TEA) inhibition was studied at the single-channel level in the KcsA potassium channel reconstituted in planar lipid bilayers. TEA acts as a fast blocker (resulting in decreased current amplitude) with an affinity in the 75 mM range even at high bandwidth. Studies ov...

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Detalhes bibliográficos
Main Authors: Kutluay, Esin, Roux, Benoît, Heginbotham, Lise
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305109/
https://ncbi.nlm.nih.gov/pubmed/15556975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052043
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