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Rapid Intracellular TEA Block of the KcsA Potassium Channel

Intracellular tetraethylammonium (TEA) inhibition was studied at the single-channel level in the KcsA potassium channel reconstituted in planar lipid bilayers. TEA acts as a fast blocker (resulting in decreased current amplitude) with an affinity in the 75 mM range even at high bandwidth. Studies ov...

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Bibliografiske detaljer
Main Authors: Kutluay, Esin, Roux, Benoît, Heginbotham, Lise
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305109/
https://ncbi.nlm.nih.gov/pubmed/15556975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052043
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