Proinsulin Shares a Motif with Interleukin-1α (IL-1α) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1

Although it has been established that diabetes increases susceptibility to infections, the role of insulin (INS) in the immune response is unknown. Here, we investigated the immunological function of INS. Proinsulin dimer (pINSd) was a potent immune stimulus that induced inflammatory cytokines, but...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Lee, Siyoung, Kim, Eunsom, Jhun, Hyunjhung, Hong, Jaewoo, Kwak, Areum, Jo, Seunghyun, Bae, Suyoung, Lee, Jongho, Kim, Busun, Lee, Jungmin, Youn, Sulah, Kim, Somi, Kim, Miyeon, Kim, Hyunwoo, Lee, Youngmin, Choi, Dong-Ki, Kim, Yong-Sung, Kim, Soohyun
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
Immunology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938183/
https://ncbi.nlm.nih.gov/pubmed/27226621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731026
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים