Contradictory Functions (Activation/Termination) of Neutrophil Proteinase 3 Enzyme (PR3) in Interleukin-33 Biological Activity

IL-1 family ligand does not possess a typical hydrophobic signal peptide and needs a processing enzyme for maturation. The maturation process of IL-33 (IL-1F11), a new member of the IL-1 family ligand, remains unclear. Precursor IL-33 ligand affinity column isolates neutrophil proteinase 3 (PR3) fro...

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Detalhes bibliográficos
Main Authors: Bae, Suyoung, Kang, Taebong, Hong, Jaewoo, Lee, Siyoung, Choi, Jida, Jhun, Hyunjhung, Kwak, Areum, Hong, Kwangwon, Kim, Eunsom, Jo, Seunghyun, Kim, Soohyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318695/
https://ncbi.nlm.nih.gov/pubmed/22270365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295055
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