Effect of Recombinant α(1)-Antitrypsin Fc-Fused (AAT-Fc)Protein on the Inhibition of Inflammatory Cytokine Production and Streptozotocin-Induced Diabetes

α(1)-Antitrypsin (AAT) is a member of the serine proteinase inhibitor family that impedes the enzymatic activity of serine proteinases, including human neutrophil elastase, cathepsin G and neutrophil proteinase 3. Here, we expressed recombinant AAT by fusing the intact AAT gene to the constant regio...

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Detalhes bibliográficos
Main Authors: Lee, Siyoung, Lee, Youngmin, Hong, Kwangwon, Hong, Jaewoo, Bae, Suyoung, Choi, Jida, Jhun, Hyunjhung, Kwak, Areum, Kim, Eunsom, Jo, Seunghyun, Dinarello, Charles A, Kim, Soohyun
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667213/
https://ncbi.nlm.nih.gov/pubmed/23552726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00308
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