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Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel

The superfamily of pentameric ligand-gated ion channels includes neurotransmitter receptors that mediate fast synaptic transmission in vertebrates, and are targets for drugs including alcohols, anesthetics, benzodiazepines and anticonvulsants. However, the mechanisms of ion channel opening, gating a...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Heusser, Stephanie A., Yoluk, Özge, Klement, Göran, Riederer, Erika A., Lindahl, Erik, Howard, Rebecca J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936957/
https://ncbi.nlm.nih.gov/pubmed/27102368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13644
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