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PrP(C) Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells

The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrP(Sc) scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrP(...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Arkhipenko, Alexander, Syan, Sylvie, Victoria, Guiliana Soraya, Lebreton, Stéphanie, Zurzolo, Chiara
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936696/
https://ncbi.nlm.nih.gov/pubmed/27389581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157991
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