PrP(C) Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells

The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrP(Sc) scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrP(...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Arkhipenko, Alexander, Syan, Sylvie, Victoria, Guiliana Soraya, Lebreton, Stéphanie, Zurzolo, Chiara
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936696/
https://ncbi.nlm.nih.gov/pubmed/27389581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157991
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