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PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells.

The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrPSc scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrPC)...

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Autores principales: Alexander Arkhipenko, Sylvie Syan, Guiliana Soraya Victoria, Stéphanie Lebreton, Chiara Zurzolo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2016-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4936696?pdf=render
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