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Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses

The APOBEC3 family of DNA cytosine deaminases has important roles in innate immunity and cancer. It is unclear how DNA tumor viruses regulate these enzymes and how these interactions, in turn, impact the integrity of both the viral and cellular genomes. Polyomavirus (PyVs) are small DNA pathogens th...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Verhalen, Brandy, Starrett, Gabriel J., Harris, Reuben S., Jiang, Mengxi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936136/
https://ncbi.nlm.nih.gov/pubmed/27147740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00771-16
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