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Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses

The APOBEC3 family of DNA cytosine deaminases has important roles in innate immunity and cancer. It is unclear how DNA tumor viruses regulate these enzymes and how these interactions, in turn, impact the integrity of both the viral and cellular genomes. Polyomavirus (PyVs) are small DNA pathogens th...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Verhalen, Brandy, Starrett, Gabriel J., Harris, Reuben S., Jiang, Mengxi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936136/
https://ncbi.nlm.nih.gov/pubmed/27147740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00771-16
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