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Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses

The APOBEC3 family of DNA cytosine deaminases has important roles in innate immunity and cancer. It is unclear how DNA tumor viruses regulate these enzymes and how these interactions, in turn, impact the integrity of both the viral and cellular genomes. Polyomavirus (PyVs) are small DNA pathogens th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Verhalen, Brandy, Starrett, Gabriel J., Harris, Reuben S., Jiang, Mengxi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936136/
https://ncbi.nlm.nih.gov/pubmed/27147740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00771-16
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