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The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer
Breast tumors often display extreme genetic heterogeneity characterized by hundreds of gross chromosomal aberrations and tens of thousands of somatic mutations. Tumor evolution is thought to be ongoing and driven by multiple mutagenic processes. A major outstanding question is whether primary tumors...
Gardado en:
| Publicado en: | Sci Adv |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5055383/ https://ncbi.nlm.nih.gov/pubmed/27730215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601737 |
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