The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

Breast tumors often display extreme genetic heterogeneity characterized by hundreds of gross chromosomal aberrations and tens of thousands of somatic mutations. Tumor evolution is thought to be ongoing and driven by multiple mutagenic processes. A major outstanding question is whether primary tumors...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Law, Emily K., Sieuwerts, Anieta M., LaPara, Kelly, Leonard, Brandon, Starrett, Gabriel J., Molan, Amy M., Temiz, Nuri A., Vogel, Rachel Isaksson, Meijer-van Gelder, Marion E., Sweep, Fred C. G. J., Span, Paul N., Foekens, John A., Martens, John W. M., Yee, Douglas, Harris, Reuben S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2016
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055383/
https://ncbi.nlm.nih.gov/pubmed/27730215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601737
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