Pharmacodynamic actions of a long-acting PTH analog (LA-PTH) in thyroparathyroidectomized (TPTX) rats and normal monkeys

Hypoparathyroidism is a disease of chronic hypocalcemia and hyperphosphatemia due to a deficiency of parathyroid hormone (PTH). PTH and analogs of the hormone are of interest as potential therapies. Accordingly, we examined the pharmacological properties of a long-acting PTH analog, [Ala(1,3,12,18,2...

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Udgivet i:J Bone Miner Res
Main Authors: Shimizu, Masaru, Joyashiki, Eri, Noda, Hiroshi, Watanabe, Tomoyuki, Okazaki, Makoto, Nagayasu, Miho, Adachi, Kenji, Tamura, Tatsuya, Potts, John T., Gardella, Thomas J., Kawabe, Yoshiki
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935665/
https://ncbi.nlm.nih.gov/pubmed/26865415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2811
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