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Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1

The regulation of hypoxia-inducible factor-1 (HIF-1) transcriptional activity in the nucleus is related to factor inhibiting HIF-1 (FIH-1). FIH-1 hydrolyzes asparagine at the C-terminal of HIF-1α, preventing the interaction between HIF-1α and its associated cofactors, and leading to suppressed activ...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Liang, Ke, Ding, Xue-qin, Lin, Chen, Kang, Y James
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935306/
https://ncbi.nlm.nih.gov/pubmed/25687434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215570821
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