Activation of Peroxisome Proliferator-activated Receptor α (PPARα) Suppresses Hypoxia-inducible Factor-1α (HIF-1α) Signaling in Cancer Cells

Activation of peroxisome proliferator-activated receptor α (PPARα) has been demonstrated to inhibit tumor growth and angiogenesis, yet the mechanisms behind these actions remain to be characterized. In this study, we examined the effects of PPARα activation on the hypoxia-inducible factor-1α (HIF-1α...

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Bibliografiset tiedot
Päätekijät: Zhou, Jundong, Zhang, Shuyu, Xue, Jing, Avery, Jori, Wu, Jinchang, Lind, Stuart E., Ding, Wei-Qun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471732/
https://ncbi.nlm.nih.gov/pubmed/22932900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367367
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