Inflammatory Pathways Are Activated during Cardiomyocyte Hypertrophy and Attenuated by Peroxisome Proliferator-activated Receptors PPARα and PPARδ

Accumulating evidence indicates an important role for inflammation in cardiac hypertrophy and failure. Peroxisome proliferator-activated receptors (PPARs) have been reported to attenuate inflammatory signaling pathways and, as such, may interfere with cardiac remodeling. Accordingly, the objectives...

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Main Authors: Smeets, Pascal J. H., Teunissen, Birgit E. J., Planavila, Anna, de Vogel-van den Bosch, Heleen, Willemsen, Peter H. M., van der Vusse, Ger J., van Bilsen, Marc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662011/
https://ncbi.nlm.nih.gov/pubmed/18701451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802143200
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