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Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1
The regulation of hypoxia-inducible factor-1 (HIF-1) transcriptional activity in the nucleus is related to factor inhibiting HIF-1 (FIH-1). FIH-1 hydrolyzes asparagine at the C-terminal of HIF-1α, preventing the interaction between HIF-1α and its associated cofactors, and leading to suppressed activ...
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| Pubblicato in: | Exp Biol Med (Maywood) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935306/ https://ncbi.nlm.nih.gov/pubmed/25687434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215570821 |
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