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Lysines in the tetramerization domain of p53 selectively modulate G1 arrest
Functional in a tetrameric state, the protein product of the p53 tumor suppressor gene confers its tumor-suppressive activity by transactivating genes which promote cell-cycle arrest, senescence, or programmed cell death. How p53 distinguishes between these divergent outcomes is still a matter of co...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934057/ https://ncbi.nlm.nih.gov/pubmed/27210019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1170270 |
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