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Cdk1-mediated phosphorylation of Cdc7 suppresses DNA re-replication
To maintain genetic stability, the entire mammalian genome must replicate only once per cell cycle. This is largely achieved by strictly regulating the stepwise formation of the pre-replication complex (pre-RC), followed by the activation of individual origins of DNA replication by Cdc7/Dbf4 kinase....
Gorde:
Argitaratua izan da: | Cell Cycle |
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Egile Nagusiak: | , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Taylor & Francis
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934051/ https://ncbi.nlm.nih.gov/pubmed/27105124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1176658 |
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