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Cdk1-mediated phosphorylation of Cdc7 suppresses DNA re-replication
To maintain genetic stability, the entire mammalian genome must replicate only once per cell cycle. This is largely achieved by strictly regulating the stepwise formation of the pre-replication complex (pre-RC), followed by the activation of individual origins of DNA replication by Cdc7/Dbf4 kinase....
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934051/ https://ncbi.nlm.nih.gov/pubmed/27105124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1176658 |
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