SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

Maintenance of genome stability requires that DNA is replicated precisely once per cell cycle. This is believed to be achieved by limiting replication origin licensing and thereby restricting the firing of each replication origin to once per cell cycle. CDC6 is essential for eukaryotic replication o...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Walter, David, Hoffmann, Saskia, Komseli, Eirini-Stavroula, Rappsilber, Juri, Gorgoulis, Vassilis, Sørensen, Claus Storgaard
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738361/
https://ncbi.nlm.nih.gov/pubmed/26818844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10530
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items