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SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

Maintenance of genome stability requires that DNA is replicated precisely once per cell cycle. This is believed to be achieved by limiting replication origin licensing and thereby restricting the firing of each replication origin to once per cell cycle. CDC6 is essential for eukaryotic replication o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Walter, David, Hoffmann, Saskia, Komseli, Eirini-Stavroula, Rappsilber, Juri, Gorgoulis, Vassilis, Sørensen, Claus Storgaard
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738361/
https://ncbi.nlm.nih.gov/pubmed/26818844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10530
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