Transferable Domain in the G(1) Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF(Cdc4) to SCF(Grr1)

Degradation of Saccharomyces cerevisiae G(1) cyclins Cln1 and Cln2 is mediated by the ubiquitin-proteasome pathway and involves the SCF E3 ubiquitin-ligase complex containing the F-box protein Grr1 (SCF(Grr1)). Here we identify the domain of Cln2 that confers instability and describe the signals in...

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Detalhes bibliográficos
Main Authors: Berset, Catherine, Griac, Peter, Tempel, Rebecca, La Rue, Janna, Wittenberg, Curt, Lanker, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133886/
https://ncbi.nlm.nih.gov/pubmed/12052857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4463-4476.2002
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