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Transferable Domain in the G(1) Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF(Cdc4) to SCF(Grr1)

Degradation of Saccharomyces cerevisiae G(1) cyclins Cln1 and Cln2 is mediated by the ubiquitin-proteasome pathway and involves the SCF E3 ubiquitin-ligase complex containing the F-box protein Grr1 (SCF(Grr1)). Here we identify the domain of Cln2 that confers instability and describe the signals in...

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Detaylı Bibliyografya
Asıl Yazarlar: Berset, Catherine, Griac, Peter, Tempel, Rebecca, La Rue, Janna, Wittenberg, Curt, Lanker, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC133886/
https://ncbi.nlm.nih.gov/pubmed/12052857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4463-4476.2002
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