Receptor for Activated C Kinase 1 (RACK1) Promotes Dishevelled Protein Degradation via Autophagy and Antagonizes Wnt Signaling

Wnt signaling plays a critical role in embryonic development, tissue homeostasis, and cancer development. Dishevelled (Dvl) is an essential and central component in Wnt signaling, and its stability and activity is tightly regulated. It has been shown that Dvl can be degraded via both the proteasome...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Cheng, Minzhang, Xue, Hua, Cao, Weipeng, Li, Wenxia, Chen, Hua, Liu, Bofeng, Ma, Benyu, Yan, Xiaohua, Chen, Ye-Guang
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2016
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933469/
https://ncbi.nlm.nih.gov/pubmed/27129200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.708818
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