Protein Kinase A-mediated 14-3-3 Association Impedes Human Dapper1 to Promote Dishevelled Degradation

Wnt signaling regulates embryo development and tissue homeostasis, and its deregulation leads to an array of diseases, including cancer. Dapper1 has been shown to be a key negative regulator of Wnt signaling. However, its function and regulation remain poorly understood. In this study, we report tha...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Hua, Liu, Linhua, Ma, Benyu, Ma, Ting Martin, Hou, Jun-Jie, Xie, Guo-Ming, Wu, Wei, Yang, Fu-Quan, Chen, Ye-Guang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083226/
https://ncbi.nlm.nih.gov/pubmed/21262972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211607
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