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MEKK2 Kinase Association with 14-3-3 Protein Regulates Activation of c-Jun N-terminal Kinase

MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family of MAP kinase kinase kinases (MAP(3)Ks). MEKK2 integrates stress and mitogenic signals to the activation of NF-κB, JNK1/2, p38, and ERK5 pathways. We have found that MEKK2 is regulated through a phosph...

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Bibliografske podrobnosti
Main Authors: Matitau, Adi E., Gabor, Timothy V., Gill, R. Montgomery, Scheid, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784737/
https://ncbi.nlm.nih.gov/pubmed/23963453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511352
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