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G(q) Protein-induced Apoptosis Is Mediated by AKT Kinase Inhibition That Leads to Protein Kinase C-induced c-Jun N-terminal Kinase Activation

G(q) protein-coupled receptors (G(q)PCRs) regulate various cellular processes, including mainly proliferation and differentiation. In a previous study we found that in prostate cancer cells, the G(q)PCR of gonadotropin-releasing hormone (GnRH) induces apoptosis by reducing the PKC-dependent AKT acti...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ben-Ami, Ido, Yao, Zhong, Naor, Zvi, Seger, Rony
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162461/
https://ncbi.nlm.nih.gov/pubmed/21757743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247726
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