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c-Jun Regulates Phosphoinositide-dependent Kinase 1 Transcription: IMPLICATION FOR Akt AND PROTEIN KINASE C ACTIVITIES AND MELANOMA TUMORIGENESIS
Mutations in N-RAS and B-RAF, which commonly occur in melanomas, result in constitutive activation of the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated protein kinase (ERK) signaling. Active ERK increases expression and activity of the c-Jun transcription factor, linking ERK...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801291/ https://ncbi.nlm.nih.gov/pubmed/19910471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.075630 |
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