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Receptor for RACK1 Mediates Activation of JNK by Protein Kinase C

Activation of the Jun-N-terminal kinase (JNK) signaling cascade by phorbol esters (TPA) or protein kinase C (PKC) is well documented, although the underlying mechanism is not known. Here, we demonstrate that the receptor for activated C kinase 1 (RACK1) serves as an adaptor for PKC-mediated JNK acti...

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Detalhes bibliográficos
Main Authors: López-Bergami, Pablo, Habelhah, Hasem, Bhoumik, Anindita, Zhang, Weizhou, Wang, Lu-Hai, Ronai, Ze’ev
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953422/
https://ncbi.nlm.nih.gov/pubmed/16061178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.06.025
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