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Requirements for PKC-augmented JNK activation by MKK4/7
The c-Jun N-terminal kinases (JNKs) are activated in response to stress, DNA damage, and cytokines by MKK4 and MKK7. We recently demonstrated that PKC can augment the degree of JNK activation by phosphorylating JNK, which requires the adaptor protein RACK1. Here we report on the conditions required...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327215/ https://ncbi.nlm.nih.gov/pubmed/18182317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.11.011 |
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