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p53 Binding Prevents Phosphatase-mediated Inactivation of Diphosphorylated c-Jun N-terminal Kinase

c-Jun N-terminal kinase (JNK) is a serine/threonine phosphotransferase whose sustained activation in response to genotoxic stress promotes apoptosis. In Drosophila, the normally rapid JNK-dependent apoptotic response to genotoxic stress is significantly delayed in Dmp53 (Drosophila p53) mutants. Lik...

詳細記述

保存先:
書誌詳細
主要な著者: Gowda, Pramod S., Zhou, Fuchun, Chadwell, Linda V., McEwen, Donald G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366850/
https://ncbi.nlm.nih.gov/pubmed/22467874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.319277
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