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Mitogen-activated Protein Kinase Phosphatase-1 Represses c-Jun NH(2)-terminal Kinase-mediated Apoptosis via NF-κB Regulation
The mechanism regulating radiation-induced anti-apoptotic response, a limiting factor in improving cell radiosensitivity, remains elusive. Mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 is the major member of MKPs that dephosphorylates and inactivates MAPK. Here we provide the evidence...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475689/ https://ncbi.nlm.nih.gov/pubmed/18508759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802229200 |
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