c-Jun NH(2)-Terminal Kinase Inhibits Targeting of the Protein Phosphatase Calcineurin to NFATc1
The protein phosphatase calcineurin is a critical mediator of calcium signals during T-cell activation. One substrate of calcineurin is the transcription factor NFATc1, which is retained in the cytoplasm of quiescent cells. NFATc1 activation requires the translocation of the transcription factor int...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.5227-5234.2000 |
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