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c-Jun NH(2)-Terminal Kinase Inhibits Targeting of the Protein Phosphatase Calcineurin to NFATc1

The protein phosphatase calcineurin is a critical mediator of calcium signals during T-cell activation. One substrate of calcineurin is the transcription factor NFATc1, which is retained in the cytoplasm of quiescent cells. NFATc1 activation requires the translocation of the transcription factor int...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Chow, Chi-Wing, Dong, Chen, Flavell, Richard A., Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2000
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.5227-5234.2000
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