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The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair

Heat shock protein 47 (HSP47) is an endoplasmic reticulum (ER)-resident collagen-specific chaperone and essential for proper formation of the characteristic collagen triple helix. It preferentially binds to the folded conformation of its clients and accompanies them from the ER to the Golgi compartm...

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Publicat a:J Biol Chem
Autors principals: Oecal, Sinan, Socher, Eileen, Uthoff, Matthias, Ernst, Corvin, Zaucke, Frank, Sticht, Heinrich, Baumann, Ulrich, Gebauer, Jan M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933464/
https://ncbi.nlm.nih.gov/pubmed/27129216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706069
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