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The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair

Heat shock protein 47 (HSP47) is an endoplasmic reticulum (ER)-resident collagen-specific chaperone and essential for proper formation of the characteristic collagen triple helix. It preferentially binds to the folded conformation of its clients and accompanies them from the ER to the Golgi compartm...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Oecal, Sinan, Socher, Eileen, Uthoff, Matthias, Ernst, Corvin, Zaucke, Frank, Sticht, Heinrich, Baumann, Ulrich, Gebauer, Jan M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933464/
https://ncbi.nlm.nih.gov/pubmed/27129216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706069
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