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The pH Sensitivity of Murine Heat Shock Protein 47 (HSP47) Binding to Collagen Is Affected by Mutations in the Breach Histidine Cluster
Heat shock protein 47 (HSP47) is a single-substrate molecular chaperone crucial for collagen biosynthesis. Although its function is well established, the molecular mechanisms that govern binding to procollagen peptides and triple helices in the endoplasmic reticulum (followed by controlled release i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567694/ https://ncbi.nlm.nih.gov/pubmed/23212911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409029 |
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