NMR and Mutational Identification of the Collagen-Binding Site of the Chaperone Hsp47

Heat shock protein 47 (Hsp47) acts as a client-specific chaperone for collagen and plays a vital role in collagen maturation and the consequent embryonic development. In addition, this protein can be a potential target for the treatment of fibrosis. Despite its physiological and pathological importa...

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Autors principals: Yagi-Utsumi, Maho, Yoshikawa, Sumi, Yamaguchi, Yoshiki, Nishi, Yohei, Kurimoto, Eiji, Ishida, Yoshihito, Homma, Takayuki, Hoseki, Jun, Nishikawa, Yoshimi, Koide, Takaki, Nagata, Kazuhiro, Kato, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457968/
https://ncbi.nlm.nih.gov/pubmed/23049894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045930
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