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Structural basis for client recognition and activity of Hsp40 chaperones
Hsp70 and Hsp40 chaperones work synergistically in a wide range of biological processes including protein synthesis, membrane translocation, and folding. We used NMR spectroscopy to determine the solution structure and dynamic features of an Hsp40 in complex with an unfolded client protein. Atomic s...
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| Publicado no: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7023980/ https://ncbi.nlm.nih.gov/pubmed/31604242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax1280 |
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