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Structural basis for the antifolding activity of a molecular chaperone
Molecular chaperones act on non-native proteins in the cell to prevent their aggregation, premature folding or misfolding. Different chaperones often exert distinct effects, such as acceleration or delay of folding, on client proteins via mechanisms that are poorly understood. Here we report the sol...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161705/ https://ncbi.nlm.nih.gov/pubmed/27501151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18965 |
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