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Structural basis for the antifolding activity of a molecular chaperone

Molecular chaperones act on non-native proteins in the cell to prevent their aggregation, premature folding or misfolding. Different chaperones often exert distinct effects, such as acceleration or delay of folding, on client proteins via mechanisms that are poorly understood. Here we report the sol...

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書目詳細資料
發表在:Nature
Main Authors: Huang, Chengdong, Rossi, Paolo, Saio, Tomohide, Kalodimos, Charalampos G.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161705/
https://ncbi.nlm.nih.gov/pubmed/27501151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18965
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