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Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver

Hemojuvelin (HJV) regulates iron homeostasis by direct interaction with bone morphogenetic protein (BMP) ligands to induce hepcidin expression through the BMP signaling pathway in the liver. Crystallography studies indicate that HJV can simultaneously bind to both BMP2 and the ubiquitously expressed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Zhao, Ningning, Maxson, Julia E., Zhang, Richard H., Wahedi, Mastura, Enns, Caroline A., Zhang, An-Sheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933279/
https://ncbi.nlm.nih.gov/pubmed/27072365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721191
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