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Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway
Systemic iron homeostasis is maintained by regulation of iron absorption in the duodenum, iron recycling from erythrocytes, and iron mobilization from the liver and is controlled by the hepatic hormone hepcidin. Hepcidin expression is induced via the bone morphogenetic protein (BMP) signaling pathwa...
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5672056/ https://ncbi.nlm.nih.gov/pubmed/28924039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801795 |
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