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Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway
Systemic iron homeostasis is maintained by regulation of iron absorption in the duodenum, iron recycling from erythrocytes, and iron mobilization from the liver and is controlled by the hepatic hormone hepcidin. Hepcidin expression is induced via the bone morphogenetic protein (BMP) signaling pathwa...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5672056/ https://ncbi.nlm.nih.gov/pubmed/28924039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801795 |
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