Carregando...
Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo
Positive strand RNA viruses replicate via a virally encoded RNA-dependent RNA polymerase (RdRP) that uses a unique palm domain active site closure mechanism to establish the canonical two-metal geometry needed for catalysis. This mechanism allows these viruses to evolutionarily fine-tune their repli...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933160/ https://ncbi.nlm.nih.gov/pubmed/27137934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726596 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|