Llwytho...

ATP IS AN ALLOSTERIC INHIBITOR OF COXSACKIEVIRUS B3 POLYMERASE

The RNA-dependent RNA polymerases from positive strand RNA viruses, such as picornaviruses and flaviviruses, close their active sites for catalysis via a unique NTP-induced conformational change in the palm domain. Combined with a fully pre-positioned templating nucleotide, this mechanism is error-p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Karr, Jonathan P., Peersen, Olve B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749642/
https://ncbi.nlm.nih.gov/pubmed/27319576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00467
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!