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Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease()

Coxsackievirus B3 is the main cause of human viral myocarditis and cardiomyopathy. Virally encoded Coxsackievirus 3C protease (3C(pro)) plays an essential role in viral proliferation. Here, benserazide was discovered as a novel inhibitor from a drug library screen targeting Coxsackievirus 3C(pro) us...

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Podrobná bibliografie
Vydáno v:FEBS Lett
Hlavní autoři: Kim, Bo-Kyoung, Cho, Joong-Heui, Jeong, Pyeonghwa, Lee, Youngjin, Lim, Jia Jia, Park, Kyoung Ryoung, Eom, Soo Hyun, Kim, Yong-Chul
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of European Biochemical Societies. Published by Elsevier B.V. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094222/
https://ncbi.nlm.nih.gov/pubmed/26022398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.05.027
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